Exceptional CO₂ tolerance in white sturgeon (Acipenser transmontanus) is associated with protection of maximum cardiac performance during hypercapnia in situ.
Identifieur interne : 002588 ( Main/Exploration ); précédent : 002587; suivant : 002589Exceptional CO₂ tolerance in white sturgeon (Acipenser transmontanus) is associated with protection of maximum cardiac performance during hypercapnia in situ.
Auteurs : Daniel W. Baker [Nouvelle-Zélande] ; Linda M. Hanson ; Anthony P. Farrell ; Colin J. BraunerSource :
- Physiological and biochemical zoology : PBZ [ 1537-5293 ]
English descriptors
- KwdEn :
- MESH :
- chemical , metabolism : Carbon Dioxide.
- physiology : Fishes, Heart.
- physiopathology : Hypercapnia.
- Adaptation, Physiological, Animals, Cardiac Output, Heart Rate.
Abstract
White sturgeon rank among the most CO₂-tolerant fish species examined to date. We investigated whether this exceptional CO₂ tolerance extended to the heart, an organ generally viewed as acidosis intolerant. Maximum cardiac output (Q(max)) and maximum cardiac power output (PO(max)) were assessed using a working, perfused, in situ heart preparation. Exposure to a Pco₂ of 3 kPa for 20 min had no significant effect on maximum cardiac performance, while exposure to 6-kPa Pco₂ reduced heart rate, Q(max), PO(max), and rate of ventricular force generation (F(O)) by 23%, 28%, 26%, and 18%, respectively; however, full recovery was observed in all these parameters upon return to control conditions. These modest impairments during exposure to 6-kPa Pco₂ were associated with partially compensated intracellular ventricular acidosis. Maximum adrenergic stimulation (500 nmol L⁻¹ adrenaline) during 6-kPa Pco₂ protected maximum cardiac performance via increased inotropy (force of contraction) without affecting heart rate. Exposure to higher CO₂ levels associated with morbidity in vivo (i.e., 8-kPa Pco₂) induced arrhythmia and a reduction in stroke volume during power assessment. Clearly, white sturgeon hearts are able to increase cardiac performance during severe hypercapnia that is lethal to other fishes. Future work focusing on atypical aspects of sturgeon cardiac function, including the lack of chronotropic response to adrenergic stimulation during hypercapnia, is warranted.
DOI: 10.1086/660038
PubMed: 21527814
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000356
- to stream PubMed, to step Curation: 000356
- to stream PubMed, to step Checkpoint: 000356
- to stream Ncbi, to step Merge: 000378
- to stream Ncbi, to step Curation: 000378
- to stream Ncbi, to step Checkpoint: 000378
- to stream Main, to step Merge: 002790
- to stream Main, to step Curation: 002588
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Exceptional CO₂ tolerance in white sturgeon (Acipenser transmontanus) is associated with protection of maximum cardiac performance during hypercapnia in situ.</title><author><name sortKey="Baker, Daniel W" sort="Baker, Daniel W" uniqKey="Baker D" first="Daniel W" last="Baker">Daniel W. Baker</name><affiliation wicri:level="1"><nlm:affiliation>School of Biological Science, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. dan.baker@auckland.ac.nz</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>School of Biological Science, University of Auckland, Private Bag 92019, Auckland 1142</wicri:regionArea><wicri:noRegion>Auckland 1142</wicri:noRegion></affiliation></author><author><name sortKey="Hanson, Linda M" sort="Hanson, Linda M" uniqKey="Hanson L" first="Linda M" last="Hanson">Linda M. Hanson</name></author><author><name sortKey="Farrell, Anthony P" sort="Farrell, Anthony P" uniqKey="Farrell A" first="Anthony P" last="Farrell">Anthony P. Farrell</name></author><author><name sortKey="Brauner, Colin J" sort="Brauner, Colin J" uniqKey="Brauner C" first="Colin J" last="Brauner">Colin J. Brauner</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="????"><PubDate><MedlineDate>2011 May-Jun</MedlineDate></PubDate></date><idno type="RBID">pubmed:21527814</idno><idno type="pmid">21527814</idno><idno type="doi">10.1086/660038</idno><idno type="wicri:Area/PubMed/Corpus">000356</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000356</idno><idno type="wicri:Area/PubMed/Curation">000356</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000356</idno><idno type="wicri:Area/PubMed/Checkpoint">000356</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000356</idno><idno type="wicri:Area/Ncbi/Merge">000378</idno><idno type="wicri:Area/Ncbi/Curation">000378</idno><idno type="wicri:Area/Ncbi/Checkpoint">000378</idno><idno type="wicri:Area/Main/Merge">002790</idno><idno type="wicri:Area/Main/Curation">002588</idno><idno type="wicri:Area/Main/Exploration">002588</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Exceptional CO₂ tolerance in white sturgeon (Acipenser transmontanus) is associated with protection of maximum cardiac performance during hypercapnia in situ.</title><author><name sortKey="Baker, Daniel W" sort="Baker, Daniel W" uniqKey="Baker D" first="Daniel W" last="Baker">Daniel W. Baker</name><affiliation wicri:level="1"><nlm:affiliation>School of Biological Science, University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. dan.baker@auckland.ac.nz</nlm:affiliation><country xml:lang="fr">Nouvelle-Zélande</country><wicri:regionArea>School of Biological Science, University of Auckland, Private Bag 92019, Auckland 1142</wicri:regionArea><wicri:noRegion>Auckland 1142</wicri:noRegion></affiliation></author><author><name sortKey="Hanson, Linda M" sort="Hanson, Linda M" uniqKey="Hanson L" first="Linda M" last="Hanson">Linda M. Hanson</name></author><author><name sortKey="Farrell, Anthony P" sort="Farrell, Anthony P" uniqKey="Farrell A" first="Anthony P" last="Farrell">Anthony P. Farrell</name></author><author><name sortKey="Brauner, Colin J" sort="Brauner, Colin J" uniqKey="Brauner C" first="Colin J" last="Brauner">Colin J. Brauner</name></author></analytic><series><title level="j">Physiological and biochemical zoology : PBZ</title><idno type="eISSN">1537-5293</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adaptation, Physiological</term><term>Animals</term><term>Carbon Dioxide (metabolism)</term><term>Cardiac Output</term><term>Fishes (physiology)</term><term>Heart (physiology)</term><term>Heart Rate</term><term>Hypercapnia (physiopathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Carbon Dioxide</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Fishes</term><term>Heart</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Hypercapnia</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adaptation, Physiological</term><term>Animals</term><term>Cardiac Output</term><term>Heart Rate</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">White sturgeon rank among the most CO₂-tolerant fish species examined to date. We investigated whether this exceptional CO₂ tolerance extended to the heart, an organ generally viewed as acidosis intolerant. Maximum cardiac output (Q(max)) and maximum cardiac power output (PO(max)) were assessed using a working, perfused, in situ heart preparation. Exposure to a Pco₂ of 3 kPa for 20 min had no significant effect on maximum cardiac performance, while exposure to 6-kPa Pco₂ reduced heart rate, Q(max), PO(max), and rate of ventricular force generation (F(O)) by 23%, 28%, 26%, and 18%, respectively; however, full recovery was observed in all these parameters upon return to control conditions. These modest impairments during exposure to 6-kPa Pco₂ were associated with partially compensated intracellular ventricular acidosis. Maximum adrenergic stimulation (500 nmol L⁻¹ adrenaline) during 6-kPa Pco₂ protected maximum cardiac performance via increased inotropy (force of contraction) without affecting heart rate. Exposure to higher CO₂ levels associated with morbidity in vivo (i.e., 8-kPa Pco₂) induced arrhythmia and a reduction in stroke volume during power assessment. Clearly, white sturgeon hearts are able to increase cardiac performance during severe hypercapnia that is lethal to other fishes. Future work focusing on atypical aspects of sturgeon cardiac function, including the lack of chronotropic response to adrenergic stimulation during hypercapnia, is warranted.</div></front></TEI><affiliations><list><country><li>Nouvelle-Zélande</li></country></list><tree><noCountry><name sortKey="Brauner, Colin J" sort="Brauner, Colin J" uniqKey="Brauner C" first="Colin J" last="Brauner">Colin J. Brauner</name><name sortKey="Farrell, Anthony P" sort="Farrell, Anthony P" uniqKey="Farrell A" first="Anthony P" last="Farrell">Anthony P. Farrell</name><name sortKey="Hanson, Linda M" sort="Hanson, Linda M" uniqKey="Hanson L" first="Linda M" last="Hanson">Linda M. Hanson</name></noCountry><country name="Nouvelle-Zélande"><noRegion><name sortKey="Baker, Daniel W" sort="Baker, Daniel W" uniqKey="Baker D" first="Daniel W" last="Baker">Daniel W. Baker</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Eau/explor/EsturgeonV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002588 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002588 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Eau
|area= EsturgeonV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:21527814
|texte= Exceptional CO₂ tolerance in white sturgeon (Acipenser transmontanus) is associated with protection of maximum cardiac performance during hypercapnia in situ.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21527814" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a EsturgeonV1
| This area was generated with Dilib version V0.6.27. |  |